ARG45220
anti-WAPL / FOE antibody
anti-WAPL / FOE antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes WAPL / FOE |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | WAPL / FOE |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human WAPL / FOE. |
| Conjugation | Un-conjugated |
| Alternate Names | WAPL; WAPL Cohesin Release Factor; KIAA0261; FOE; WAPAL; Wings Apart-Like Protein Homolog; Friend Of EBNA2 Protein; Friend Of EBNA2 (Epstein-Barr Virus Nuclear Protein 2); Wings Apart-Like Homolog (Drosophila); Friend Of EBNA2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 180 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | WAPL |
| Gene Full Name | WAPL Cohesin Release Factor |
| Background | Enables ATP-dependent protein-DNA unloader activity. Involved in several processes, including mitotic sister chromatid segregation; negative regulation of DNA replication; and negative regulation of sister chromatid cohesion. Located in several cellular components, including intercellular bridge; mitotic spindle; and nucleoplasm. [provided by Alliance of Genome Resources, Nov 2024] |
| Function | Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. [UniProt] |
| Cellular Localization | Chromosome; Cytoplasm; Nucleus. [UniProt] |
| Calculated MW | 133 kDa |
| PTM | Acetylation; Phosphoprotein. [UniProt] |
