Overview

Product Description	Mouse Monoclonal antibody recognizes WDR59
Tested Reactivity	Hu
Tested Application	WB
Host	Mouse
Clonality	Monoclonal
Isotype	IgG2a
Target Name	WDR59
Antigen Species	Human
Epitope	RKQKEGSKDY QLVTWSRDQT LRMWRVDSQM QRLCANDILD GVDEFIESIS LLPEPEKTLH TEDTDHQHTA SHGEEEALKE DPPRNLLEER KSDQLGLPQT
Conjugation	Un-conjugated
Alternate Names	WDR59; WD Repeat Domain59; WD Repeat-Containing Protein59; GATOR2 Complex Protein WDR59; FLJ12270; GATOR Complex Protein WDR59; CDw12 Antigen; KIAA1923; P90-120; CDW12; FP977

Application Instructions

Application Suggestion	Tested Application Dilution WB 1:2000
Application Note	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form	Liquid
Purification	Protein A purification
Buffer	PBS with0.09% sodium azide
Preservative	0.09% sodium azide
Storage Instruction	For continuous use, store undiluted antibody at2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 79726 Human WDR59 Swiss-port # Q6PJI9 Human WD repeat-containing protein 59
Gene Symbol	WDR59
Gene Full Name	WD Repeat Domain59
Background	Involved in cellular response to amino acid starvation and positive regulation of TOR signaling. Located in lysosomal membrane. Part of GATOR2 complex. [provided by Alliance of Genome Resources, Apr2022]
Function	In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. [Uniprot]
Cellular Localization	Lysosome, Membrane. [Uniprot]
PTM	Phosphoprotein. [Uniprot]

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