ARG45834

anti-Zebrafish MLN51 / CASC3 antibody

anti-Zebrafish MLN51 / CASC3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Zebrafish

Overview

Product Description Rabbit Polyclonal antibody recognizes MLN51 / CASC3
Tested Reactivity Zfsh
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name MLN51 / CASC3
Antigen Species Zebrafish
Conjugation Un-conjugated
Alternate Names CASC3; CASC3 Exon Junction Complex Subunit; The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P2-5 μg/ml
WB0.1-0.5 μg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 76 kDa

Properties

Form Liquid
Purification Affinity chromatography purified
Buffer 0.02M PBS, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% glycerol
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 403025 Zebrafish CASC3

Swiss-port # Q1ECZ4 Zebrafish Protein CASC3

Gene Symbol CASC3
Gene Full Name CASC3 Exon Junction Complex Subunit
Background Required for pre-mRNA splicing as component of the spliceosome.
Cellular Localization Cell projection; Cytoplasm; Nucleus; Spliceosome. [UniProt]
Calculated MW 76 kDa
PTM ADP-ribosylation; Phosphoprotein; Ubl conjugation. [UniProt]