ARG45858
anti-Zebrafish SIAH1 antibody
anti-Zebrafish SIAH1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Zebrafish
Overview
| Product Description | Rabbit Polyclonal antibody recognizes SIAH1 |
|---|---|
| Tested Reactivity | Zfsh |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | SIAH1 |
| Antigen Species | Zebrafish |
| Conjugation | Un-conjugated |
| Alternate Names | SIAH1; Siah E3 Ubiquitin Protein Ligase 1; RING-Type E3 Ubiquitin Transferase SIAH1; E3 Ubiquitin-Protein Ligase SIAH1; Seven In Absentia Homolog 1; Siah-1a; HSIAH1; Seven In Absentia Homolog 1 (Drosophila); EC 2.3.2.27; EC 6.3.2 47; HUMSIAH; BURHAS; SIAH1A; Siah-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity chromatography purified |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.02% Sodium azide and 50% glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% glycerol |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q7ZVG6 Zebrafish E3 ubiquitin-protein ligase Siah1 |
|---|---|
| Gene Symbol | SIAH1 |
| Gene Full Name | Siah E3 Ubiquitin Protein Ligase 1 |
| Background | This gene belongs to the cadherin superfamily of calcium-dependent cell adhesion molecules. The encoded protein is a photoreceptor-specific cadherin that plays a role in outer segment disc morphogenesis. Mutations in this gene are associated with inherited retinal dystrophies. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2013] |
| Function | E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. [UniProt] |
| Calculated MW | 37 kDa |
