ARG54077
anti-hnRNP U antibody
anti-hnRNP U antibody for Western blot and Human
Gene Regulation antibody
Overview
| Product Description | Mouse Monoclonal antibody recognizes HNRNPU |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | hnRNP U |
| Antigen Species | Human |
| Immunogen | Purified recombinant human hnRNP U protein fragments expressed in E.coli. |
| Conjugation | Un-conjugated |
| Alternate Names | U21.1; p120; hnRNP U; Heterogeneous nuclear ribonucleoprotein U; SAFA; HNRPU; SAF-A; pp120; Scaffold attachment factor A |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | 110 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.1M Tris-Glycine (pH 7.4), 150 mM NaCl, 0.2% Sodium azide and 50% Glycerol |
| Preservative | 0.2% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q00839 Human Heterogeneous nuclear ribonucleoprotein U |
|---|---|
| Gene Symbol | HNRNPU |
| Gene Full Name | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| Background | Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single-stranded DNA and RNA. |
| Function | Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single-stranded DNA and RNA. Plays a role in the circadian regulation of the core clock component ARNTL/BMAL1 transcription (By similarity). [UniProt] |
| Cellular Localization | Nucleus. Cytoplasm. Cell surface. |
| Research Area | Gene Regulation antibody |
| Calculated MW | 91 kDa |
| PTM | Extensively phosphorylated. Arg-739 is dimethylated, probably to asymmetric dimethylarginine. Citrullinated by PADI4. |
Images (1) Click the Picture to Zoom In
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ARG54077 anti-hnRNP U antibody WB image
Western blot: Jurkat cell lysate stained with ARG54077 anti-hnRNP U antibody at 1:1000 dilution.
