ARG83547
arigoQIK® Mouse CD279 / PD-1 ELISA Development Kit
arigoQIK® Mouse CD279 / PD-1 ELISA Development Kit for ELISA and Mouse
Overview
| Product Description | ARG83547 arigoQIK® Mouse CD279 / PD-1 ELISA Development Kit, includes Capture antibody, Detection antibody, Standard, and HRP-Streptavidin Solution. This ELISA Development Kit is designed for the development of sandwich ELISA to measure Mouse CD279 / PD-1 in serum, plasma and cell culture supernatants. For other reagents required for arigoQIK® ELISA Development Kit, please refer ARG83524 Integral Reagent Kit (ELISA Development Kit) More about arigoQIK® : ● Optimized capture and detection antibody pairs ● Reduced incubation time and wash cycles ● 2-hour quicker than conventional ELISA process ● 5- and 15-plate packages available |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ELISA |
| Target Name | CD279 / PD-1 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 31.25 pg/ml |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 62.50 - 4000pg/ml |
| Sample Volume | 50 μl |
| Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 10% |
| Alternate Names | PDCD1; Programmed Cell Death 1; PD1; CD279; HSLE1; PD-1; Systemic Lupus Erythematosus Susceptibility 2; Programmed Cell Death Protein 1; Protein PD-1; SLEB2; HPD-1; Programmed Cell Death 1 Protein; CD279 Antigen; HPD-L |
Properties
| Storage Instruction | Store components at 4°C or -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | PDCD1 |
|---|---|
| Gene Full Name | Programmed Cell Death 1 |
| Background | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] |
| Function | The blockage of the PDCD1-mediated pathway results in the reversal of the exhausted T-cell phenotype and the normalization of the anti-tumor response, providing a rationale for cancer immunotherapy. [UniProt] |
| Cellular Localization | Cell membrane, Membrane. [UniProt] |
| Highlight | Related news: arigoQIK, DIY your sandwich ELISA kits; |
| PTM | Disulfide bond, Glycoprotein, Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt] |
| Title | Download Link |
|---|---|
| ARG83547 arigoQIK® Mouse CD279 / PD-1 ELISA Development Kit User manual |
 Download
|
