ARG30265
AP-1 early response transcription factor Antibody Duo (c-Jun, c-Fos)
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG54081 | anti-c-Jun antibody | Mouse mAb | Hu | WB | 50 μl |
| ARG54149 | anti-c-Fos antibody | Mouse mAb | Hu, Ms, Rat, Mk | WB | 50 μl |
Overview
| Product Description | c-fos (encodes a 62 kDa protein) forms heterodimer with c-jun (part of Jun family of transcription factors), resulting in the formation of AP-1 (Activator Protein-1) complex which binds DNA at AP-1 specific sites at the promoter and enhancer regions of target genes and converts extracellular signals into changes of gene expression. AP-1 transcription factor complex is activated by various cytokines, growth factors, stress and infections. Upon activation, AP-1 turns on a number of cellular processes including differentiation, proliferation and apoptosis. Curran. J Exp Med (1992) 168: 169 Angel and Karin. BBA (1991) 1072: 129 |
|---|---|
| Target Name | AP-1 early response transcription factor |
| Alternate Names | AP-1 early response transcription factor antibody; c-Jun antibody; c-Fos antibody |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
