ARG83003

Arg8 Vasopressin ELISA Kit

Arg8 Vasopressin ELISA Kit for ELISA and Dog,Human,Mouse,Rat,Sheep

Overview

Product Description ARG83003 Arg8 Vasopressin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human, Mouse, Rat, Sheep, Dog Arg8 Vasopressin in plasma.
Tested Reactivity Hu, Ms, Rat, Dog, Sheep
Tested Application ELISA
Specificity Cross-Reactivity:
[Arg8]-Vasopressin (Human, Mouse, Rat, Ovine, Canine): 100%; [Arg8]-Vasotocin: 54%; [Lys8]-Vasopressin (Human, Rat, Mouse, Ovine), Deamino-[D-Arg8]-Vassopressin, Oxytocin, LH-RH, ACTH (Human), alpha-ANP (1-28) (Human, Canine), Met-Enkephalin, PACAP38 (Human, Ovine, Rat) and PACAP27-NH2 (Human, Ovine, Rat): 0%.
Target Name Arg8 Vasopressin
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Protein Full Name Arginine vasopressin
Sensitivity 0.04 ng/ml
Detection Range 0.04 - 0.51 ng/ml
Sample Type Plasma (Sample extraction is recommended)
Standard Range 0.01 - 100 ng/ml
Sample Volume 50 µl
Precision Intra-assay: < 10%
Inter-assay: < 15%
Alternate Names Arginine-vasopressin; Vasopressin-neurophysin 2-Arg8 Vasopressin; Neurophysin-II; AVP; Arginine Vasopressin; ARVP; ADH; Prepro-Arginine-Vasopressin-Neurophysin II; Vasopressin-Neurophysin 2-Copeptin; Antidiuretic Hormone; Neurohypophyseal; Prepro-AVP-NP; Copeptin; AVP-NPII; VP; Vasopressin-Neurophysin II-Copeptin; Diabetes Insipidus; Neurophysin II; AVRP

Application Instructions

Assay Time ~ 4 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use. This kit cannot ship or deliver to addresses in the following countries: Argentina, Austria, Belgium, China, France, Germany, Hungary, India, Italy, Japan, Liechtenstein, Luxembourg, Mexico, Spain, Switzerland, United Kingdom. Due to the assay method performed by this product is covered by Patent No. EP1738178 in these countries.

Bioinformation

Database Links

GeneID: 11998 Mouse AVP

GeneID: 24221 Rat AVP

GeneID: 551 Human AVP

Gene Symbol AVP
Gene Full Name arginine vasopressin
Background This gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, Arg8 Vasopressin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). [provided by RefSeq, Mar 2010]
Function Arg-vasopressin has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels. Acts by binding to vasopressin receptors (V1bR/AVPR1B, V1aR/AVPR1A, and V2R/AVPR2) (PubMed:18174156) [UniProt]
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