ARG82125
Corticotropin Releasing Factor ELISA Kit
Corticotropin Releasing Factor ELISA Kit for ELISA and Cat,Dog,Human,Mouse,Rat
Overview
Product Description | ARG82125 Corticotropin Releasing Factor ELISA Kit is an Enzyme Immunoassay kit for the quantification of Corticotropin Releasing Factor in serum and plasma. |
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Tested Reactivity | Hu, Ms, Rat, Cat, Dog |
Species Does Not React With | Bov, Sheep |
Tested Application | ELISA |
Specificity | Cross Reactivity: CRF (Human, Rat): 100% CRF (Sheep, Bovine), Prepro-CRF (125-151, Human), PACAP-38 (Human, Rat, Sheep), LH-RH, ACTH (Human), [Arg8]-Vasopressin and BNP-45 (Rat): 0% |
Target Name | Corticotropin Releasing Factor |
Conjugation | HRP |
Conjugation Note | Substrate: TMB and read at 450 nm. |
Sensitivity | 0.33 ng/ml |
Detection Range | 0.33 - 3.73 ng/ml |
Sample Type | Serum and plasma. |
Standard Range | 0.01 - 100 ng/ml |
Sample Volume | 100 µl |
Precision | Intra-Assay CV: < 10% Inter-Assay CV: < 15% |
Alternate Names | Corticoliberin; Corticotropin-releasing hormone; CRF; CRH1; Corticotropin-releasing factor |
Application Instructions
Assay Time | 4 hours |
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Properties
Form | 96 well |
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Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | CRH |
Gene Full Name | corticotropin releasing hormone |
Background | Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010] |
Function | This hormone from hypothalamus regulates the release of corticotropin from pituitary gland. [UniProt] |
Cellular Localization | Secreted. [UniProt] |
Highlight | Related products: Corticotropin Releasing Factor antibodies; Corticotropin Releasing Factor ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
Title | Download Link |
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ARG82125 Corticotropin Releasing Factor ELISA Kit User manual | Download |