ARG81394
Hsp90 alpha ELISA kit
Hsp90 alpha ELISA kit for ELISA and Human,Goat
Overview
| Product Description | ARG81394 Hsp90 alpha ELISA kit is an Enzyme Immunoassay kit for the quantification of Hsp90 alpha in serum, cell lysates and tissue lysates. |
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| Tested Reactivity | Hu, Goat |
| Tested Application | ELISA |
| Target Name | Hsp90 alpha |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 0.117 ng/ml |
| Sample Type | Serum, cell lysates and tissue lysates. |
| Standard Range | 0.44 - 28 ng/ml |
| Sample Volume | 100 µl |
| Alternate Names | EL52; Hsp90; HSPC1; Heat shock 86 kDa; LAP-2; HSP90N; LAP2; HSP90A; HSPCAL4; HSP89A; HSP86; HSP 86; HSPCA; Lipopolysaccharide-associated protein 2; HSPCAL1; LPS-associated protein 2; HSPN; Renal carcinoma antigen NY-REN-38; Heat shock protein HSP 90-alpha; Hsp89 |
Application Instructions
| Assay Time | ~ 3 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | HSP90AA1 |
| Gene Full Name | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| Background | The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| Function | Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. [UniProt] |
| Cellular Localization | Nucleus. Cytoplasm. Melanosome. Cell membrane. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. [UniProt] |
| Highlight | Related products: Hsp90 alpha antibodies; Hsp90 alpha ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| PTM | ISGylated. S-nitrosylated; negatively regulates the ATPase activity and the activation of eNOS by HSP90AA1. [UniProt] |
| Title | Download Link |
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| ARG81394 Hsp90 alpha ELISA kit User manual |
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