ARG82276
Human Apolipoprotein H ELISA Kit
Human Apolipoprotein H ELISA Kit for ELISA and Human,Primates
Overview
| Product Description | ARG82276 Human Apolipoprotein H ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Apolipoprotein H in serum, plasma and cell culture supernatants. |
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| Tested Reactivity | Hu, NHuPrm |
| Tested Application | ELISA |
| Specificity | Cross-react with apoH from non-human primates. |
| Target Name | Apolipoprotein H |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 0.02 ng/ml |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 0.02 - 15 ng/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: 2.7% Inter-Assay CV: 3.4% |
| Alternate Names | Apo-H; Beta-2-glycoprotein 1; BG; B2G1; APC inhibitor; Apolipoprotein H; Anticardiolipin cofactor; B2GPI; Beta; 2; Activated protein C-binding protein; B2GP1; Beta-2-glycoprotein I |
Application Instructions
| Assay Time | ~ 4.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
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| Gene Symbol | APOH |
| Gene Full Name | apolipoprotein H (beta-2-glycoprotein I) |
| Background | Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq, Jul 2008] |
| Function | Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Highlight | Related products: Apolipoprotein antibodies; Apolipoprotein ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| PTM | N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele. [UniProt] |
| Title | Download Link |
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| ARG82276 Human Apolipoprotein H ELISA Kit User's manual |
 Download
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