ARG80905

Human BD-1 / beta Defensin-1 ELISA kit

Human BD-1 / beta Defensin-1 ELISA kit for ELISA and Human

Microbiology and Infectious Disease kit

Overview

Product Description ARG80905 Human BD-1 / beta Defensin-1 ELISA kit is a Enzyme Immunoassay kit for the quantification of Human BD-1 / beta Defensin-1 in serum, plasma and cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity No significant cross-reactivity or interference with BD-2, BD-3, BD-4.
Target Name BD1 / beta Defensin 1
Conjugation HRP
Conjugation Note

Substrate: TMB and read at 450 nm

Sensitivity 0.8 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 1.56 - 100 pg/ml
Sample Volume 100 µl
Precision

CV: <10%

Alternate Names DEFB-1; Defensin, beta 1; HBD1; hBD-1; BD1; Beta-defensin 1; DEFB101; BD-1

Application Instructions

Assay Time 4 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol DEFB1
Gene Full Name defensin, beta 1
Background Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. Beta Defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]
Function Beta Defensin 1 has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636). [UniProt]
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Research Area Microbiology and Infectious Disease kit
Title Download Link
ARG80905 Human BD-1 / beta Defensin-1 ELISA kit User's manual download icon Download