ARG80905
Human BD-1 / beta Defensin-1 ELISA kit
Human BD-1 / beta Defensin-1 ELISA kit for ELISA and Human
Microbiology and Infectious Disease kit
Overview
| Product Description | ARG80905 Human BD-1 / beta Defensin-1 ELISA kit is a Enzyme Immunoassay kit for the quantification of Human BD-1 / beta Defensin-1 in serum, plasma and cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | No significant cross-reactivity or interference with BD-2, BD-3, BD-4. |
| Target Name | BD1 / beta Defensin 1 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm |
| Sensitivity | 0.8 pg/ml |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 1.56 - 100 pg/ml |
| Sample Volume | 100 µl |
| Precision | CV: <10% |
| Alternate Names | DEFB-1; Defensin, beta 1; HBD1; hBD-1; BD1; Beta-defensin 1; DEFB101; BD-1 |
Application Instructions
| Assay Time | 4 hours |
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Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | DEFB1 |
|---|---|
| Gene Full Name | defensin, beta 1 |
| Background | Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. Beta Defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008] |
| Function | Beta Defensin 1 has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636). [UniProt] |
| Highlight | Related products: beta Defensin1 antibodies; beta Defensin1 ELISA Kits; Related news: New MMP7 (total or active) ELISA kits are released New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Research Area | Microbiology and Infectious Disease kit |
| Title | Download Link |
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| ARG80905 Human BD-1 / beta Defensin-1 ELISA kit User's manual |
 Download
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