ARG82974

Human BMP4 ELISA Kit

Human BMP4 ELISA Kit for ELISA and Human

Overview

Product Description ARG82974 Human BMP4 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human BMP4 in serum, plasma, cell culture supernatant samples.
Tested Reactivity Hu
Tested Application ELISA
Specificity Cross-Reactivity: Not reacts with Human BMPR-IB/FChimera, BMP5, BMP6, BMP7 and BMP8 proteins.
Target Name BMP4
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 7.8 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 15.6 - 1000 pg/ml
Sample Volume 100 µl
Precision Intra-Assay CV: < 10%
Inter-Assay CV: < 10%
Alternate Names BMP2B; BMP-4; OFC11; Bone morphogenetic protein 2B; BMP2B1; Bone morphogenetic protein 4; MCOPS6; ZYME; BMP-2B

Application Instructions

Assay Time ~ 4 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 652 Human BMP4

Swiss-port # P12644 Human Bone morphogenetic protein 4

Gene Symbol BMP4
Gene Full Name bone morphogenetic protein 4
Background The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq, Jul 2008]
Function Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). [UniProt]
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BMP antibodies; BMP ELISA Kits; BMP recombinant proteins;
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