ARG80904
Human Betacellulin / BTC ELISA kit
Human Betacellulin / BTC ELISA kit for ELISA and Human
Signaling Transduction kit
Overview
| Product Description | ARG80904 Human Betacellulin / BTC ELISA kit is a Enzyme Immunoassay kit for the quantification of Human Betacellulin / BTC in Serum, Plasma, Cell culture supernatants |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | No significant cross-reactivity or interference with EGF, Epigen, Epiregulin, HB-EGF, Heregulinβ-1, Prokineticin-2, TGF-α. |
| Target Name | BTC / Betacellulin |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm |
| Sensitivity | 15 pg/ml |
| Sample Type | Serum, Plasma, Cell culture supernatants |
| Standard Range | 31.25 - 2000 pg/ml |
| Sample Volume | 100 µl |
| Precision | CV: <10% |
| Alternate Names | Probetacellulin; BTC |
Application Instructions
| Assay Time | 4 hours |
|---|
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | BTC |
|---|---|
| Gene Full Name | betacellulin |
| Background | Betacellulin (BTC) is a member of epidermal growth factor (EGF) family, synthesized primarily as transmembrane precursors. The precursor form of BTC are processed to mature molecules by proteolytic events. The mature Betacellulin (BTC) is one of a ligand for the EGFR/ErbB receptor tyrosine kinases, and play roles in cell growth and differentiation. BTC may also play a protective role in acute pancreatitis, whereas increased expression of BTC may contribute to diabetic macular edema. Gene therapy using combinations of BTC and other pancreas-specific transcription factors may induce islet neogenesis and remediate hyperglycemia in type 1 diabetes. [modified from RefSeq, Apr 2011] |
| Function | Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. [UniProt] |
| Highlight | Related products: Betacellulin antibodies; Betacellulin ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Research Area | Signaling Transduction kit |
| Title | Download Link |
|---|---|
| ARG80904 Human Betacellulin / BTC ELISA kit User's manual |
 Download
|
