ARG80096

Human CCL19 / MIP-3 beta ELISA Kit

Human CCL19 / MIP-3 beta ELISA Kit for ELISA and Human

Overview

Product Description ARG80096 Human CCL19 / MIP-3 beta ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CCL19 / MIP-3 beta in serum, plasma and cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity Cross-Reactivity: Not reacts with Human MIP-3 alpha, Mouse MIP-3 alpha, Mouse MIP-3 beta and Rat MIP-3 alpha.
Target Name CCL19 / MIP-3 beta
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 7.8 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 15.6 - 1000 pg/ml
Sample Volume 100 µl
Precision Intra-Assay CV: < 10%
Inter-Assay CV: < 10%
Alternate Names Small-inducible cytokine A19; EBI1 ligand chemokine; CKb11; SCYA19; ELC; MIP-3b; MIP3B; C-C motif chemokine 19; Macrophage inflammatory protein 3 beta; Epstein-Barr virus-induced molecule 1 ligand chemokine; Beta-chemokine exodus-3; CK beta-11; MIP-3-beta

Application Instructions

Assay Time ~ 3.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6363 Human CCL19

Swiss-port # Q99731 Human C-C motif chemokine 19

Gene Symbol CCL19
Gene Full Name chemokine (C-C motif) ligand 19
Background This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014]
Function May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. [UniProt]
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Title Download Link
ARG80096 Human CCL19 / MIP-3 beta ELISA Kit User manual download icon Download