ARG81266

Human CCL20 / MIP-3 alpha ELISA Kit

Human CCL20 / MIP-3 alpha ELISA Kit for ELISA and Human

Overview

Product Description ARG81266 Human CCL20 / MIP-3 alpha ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CCL20 / MIP-3 alpha in serum, plasma or cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Target Name CCL20 / MIP3 alpha
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 7 pg/ml
Sample Type Serum, plasma or cell culture supernatants.
Standard Range 15.6 - 1000 pg/ml
Sample Volume 100 µl
Alternate Names ST38; CC chemokine LARC; Exodus; Macrophage inflammatory protein 3 alpha; 2-70; MIP-3a; Beta-chemokine exodus-1; SCYA20; MIP-3-alpha; LARC; MIP3A; 1-64; Small-inducible cytokine A20; 1-67; CKb4; C-C motif chemokine 20; Liver and activation-regulated chemokine

Application Instructions

Assay Time ~ 3.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6364 Human CCL20

Swiss-port # P78556 Human C-C motif chemokine 20

Gene Symbol CCL20
Gene Full Name chemokine (C-C motif) ligand 20
Background This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Function Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213. [UniProt]
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PTM C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Title Download Link
ARG81266 Human CCL20 / MIP-3 alpha ELISA Kit User's manual download icon Download