ARG81331

Human CD261 / TRAIL-R1 ELISA Kit

Human CD261 / TRAIL-R1 ELISA Kit for ELISA and Human

Overview

Product Description ARG81331 Human CD261 / TRAIL-R1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD261 / TRAIL-R1 in serum, plasma and cell culture supernatant.
Tested Reactivity Hu
Tested Application ELISA
Specificity Specific for Human CD261 / TRAIL-R1. No cross reactivity observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R2, TRAIL R3, TRAIL R4, CD178 and Granzyme B.
Target Name CD261 / TRAIL R1
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 8 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 31.25 - 1000 pg/ml
Sample Volume 100 µl
Alternate Names TNF-related apoptosis-inducing ligand receptor 1; CD antigen CD261; TRAILR-1; DR4; Tumor necrosis factor receptor superfamily member 10A; CD261; Death receptor 4; APO2; TRAIL receptor 1; TRAIL-R1; TRAILR1

Application Instructions

Assay Time ~ 2.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 8797 Human TNFRSF10A

Swiss-port # O00220 Human Tumor necrosis factor receptor superfamily member 10A

Gene Symbol TNFRSF10A
Gene Full Name tumor necrosis factor receptor superfamily, member 10a
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Function Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. [UniProt]
Highlight Related products:
CD261 antibodies; CD261 ELISA Kits;
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Title Download Link
ARG81331 Human CD261 / TRAIL-R1 ELISA Kit User's manual download icon Download