ARG81332
Human CD262 / TRAIL-R2 ELISA Kit
Human CD262 / TRAIL-R2 ELISA Kit for ELISA and Human
Overview
| Product Description | ARG81332 Human CD262 / TRAIL-R2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD262 / TRAIL-R2 in serum, plasma and cell culture supernatant. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | Specific for Human CD262 / TRAIL-R2. No cross reactivity was observed with TRAIL, CD117, IL-6R, IL-2R, CD116, TRAIL R1, TRAIL R3, TRAIL R4, CD178 and Granzyme B. |
| Target Name | CD262 / TRAIL R2 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 6 pg/ml |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 31.25 - 1000 pg/ml |
| Sample Volume | 100 µl |
| Alternate Names | TRICK2A; TRICK2B; KILLER; TRAILR2; TNF-related apoptosis-inducing ligand receptor 2; DR5; CD antigen CD262; TRICK2; CD262; KILLER/DR5; Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; TRAIL-R2; TRAIL receptor 2; TRICKB; ZTNFR9 |
Application Instructions
| Assay Time | ~ 2.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O14763 Human Tumor necrosis factor receptor superfamily member 10B |
|---|---|
| Gene Symbol | TNFRSF10B |
| Gene Full Name | tumor necrosis factor receptor superfamily, member 10b |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009] |
| Function | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. [UniProt] |
| Highlight | Related products: CD262 antibodies; CD262 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Title | Download Link |
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| ARG81332 Human CD262 / TRAIL-R2 ELISA Kit User's manual |
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