ARG81270

Human CD62P / P-Selectin ELISA Kit

Human CD62P / P-Selectin ELISA Kit for ELISA and Human

publication_link Publication1

Overview

Product Description ARG81270 Human CD62P / P-Selectin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD62P / P-Selectin in serum, plasma or cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Target Name CD62P / P-Selectin
Conjugation HRP
Conjugation Note

Substrate: TMB and read at 450 nm.

Sensitivity 62 pg/ml
Sample Type Serum, plasma or cell culture supernatants.
Standard Range 125 - 8000 pg/ml
Sample Volume 100 µl
Alternate Names PADGEM; CD62; Platelet activation dependent granule-external membrane protein; CD62 antigen-like family member P; GMP140; PSEL; Granule membrane protein 140; CD62P; CD antigen CD62P; Leukocyte-endothelial cell adhesion molecule 3; GRMP; GMP-140; P-selectin; LECAM3

Application Instructions

Assay Time ~ 3.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6403 Human SELP

Swiss-port # P16109 Human P-selectin

Gene Symbol SELP
Gene Full Name selectin P (granule membrane protein 140kDa, antigen CD62)
Background This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]
Function Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. [UniProt]
Highlight Related products:
CD62 antibodies; CD62 ELISA Kits;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData

Specific References

Prognostic value of serum levels of multiple adhesion factors in patients with sepsis-induced acute kidney injury

ELISA / Human / Serum

Yan Li et al.
Int Urol Nephrol,  (2022)

publication_link

 

hr_line
Title Download Link
ARG81270 Human CD62P / P-selectin ELISA Kit User's manual download icon Download