ARG83239
Human CD79b ELISA Kit
Human CD79b ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83239 Human CD79b ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD79b in Serum, Plasma and Cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | CD79b |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 15 pg/ml |
| Detection Range | 15.6 pg/ml - 1,000 pg/ml |
| Sample Type | Serum, Plasma and Cell culture supernatants |
| Precision | Intra-Assay CV: 6.4% Inter-Assay CV: 6.3% |
| Alternate Names | B29; B-cell-specific glycoprotein B29; Ig-beta; B-cell antigen receptor complex-associated protein beta chain; Immunoglobulin-associated B29 protein; AGM6; IGB; CD antigen CD79b |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P40259 Human B-cell antigen receptor complex-associated protein beta chain |
|---|---|
| Gene Symbol | CD79B |
| Gene Full Name | CD79b molecule, immunoglobulin-associated beta |
| Background | The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| Function | Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. [UniProt] |
| PTM | Phosphorylated on tyrosine upon B-cell activation by SRC-type Tyr-kinases such as BLK, LYN and SYK. |
| Title | Download Link |
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| ARG83239 Human CD79b ELISA Kit User manual |
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