ARG83248
Human CEACAM3 ELISA Kit
Human CEACAM3 ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83248 Human CEACAM3 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CEACAM3 in Serum, Plasma and Cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | CEACAM3 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 13 pg/ml |
| Detection Range | 15.6 pg/ml - 1,000 pg/ml |
| Sample Type | Serum, Plasma and Cell culture supernatants |
| Precision | Intra-Assay CV: 2.7% Inter-Assay CV: 4.2% |
| Alternate Names | CGM1; W282; Carcinoembryonic antigen CGM1; CEA; Carcinoembryonic antigen-related cell adhesion molecule 3; W264; CD66D; CD antigen CD66d |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P40198 Human Carcinoembryonic antigen-related cell adhesion molecule 3 |
|---|---|
| Gene Symbol | CEACAM3 |
| Gene Full Name | carcinoembryonic antigen-related cell adhesion molecule 3 |
| Background | This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013] |
| Function | Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis. [UniProt] |
| Cellular Localization | Membrane, Single-pass type I membrane protein. [UniProt] |
| PTM | Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected. [UniProt] |
| Title | Download Link |
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| ARG83248 Human CEACAM3 ELISA Kit User manual |
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