ARG82612

Human CTGF ELISA Kit

Human CTGF ELISA Kit for ELISA and Human

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Overview

Product Description ARG82612 Human CTGF ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CTGF in serum, plasma and cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity This kit could assay both natural and recombinant Human CTGF.

No significant cross-reactivity or interference was observed in the following samples:
Human: IFN gamma, IL1 beta, IL2, IL4, IL5, IL6, IL8, IL10, IL12, IL17A, IL18, IL21, IL22, IL23, MCP1, TGF beta 1, TNF alpha and VEGF.
Mouse: IFN gamma, IL1 beta, IL2, IL4, IL6, IL10, IL17A and TNF alpha.
Rat: IFN gamma, IL1 beta, IL4, IL6, IL10 and TNF alpha.
Target Name CTGF
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 31.3 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 62.5 - 4000 pg/ml
Sample Volume 50 - 100 µl
Precision Intra-Assay CV: 5.8%
Inter-Assay CV: 6.9%
Alternate Names Insulin-like growth factor-binding protein 8; IGFBP-8; CCN2; IBP-8; HCS24; Connective tissue growth factor; IGF-binding protein 8; CCN family member 2; IGFBP8; Hypertrophic chondrocyte-specific protein 24; NOV2

Application Instructions

Assay Time ~ 3.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1490 Human CTGF

Swiss-port # P29279 Human Connective tissue growth factor

Gene Symbol CTGF
Gene Full Name connective tissue growth factor
Background The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]
Function Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. [UniProt]
Cellular Localization Secreted, extracellular space, extracellular matrix. Secreted. [UniProt]
Highlight Related products:
CTGF antibodies; CTGF ELISA Kits;
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Simplify the ELISA analysis by GainData

Specific References

Hepatocyte growth factor exhibits anti-fibrotic effects in an in vitro model of nifedipine-induced gingival overgrowth

ELISA / Human / Cell culture supernatants

Kei Yamazaki et al.
J Oral Sci.,  (2022)

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