ARG81397

Human CXCL3 / GRO gamma ELISA Kit

Human CXCL3 / GRO gamma ELISA Kit for ELISA and Human

Overview

Product Description ARG81397 Human CXCL3 / GRO gamma ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CXCL3 / GRO gamma in serum, plasma and cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity The following recombinant Human proteins exhibited no cross-reactivity or interference: BMP1, BMP2, BMP4, HGF, IL-1 beta, IL-1RA, IL-2, IL-4, IL-5, sLHR, IL-8, IL-10, IL-12, IL-13, IL15, IFN gamma, MMP2, MMP9, IL2R, TGFβ1, TGFβ2, TGFβ3, TLR1, TLR2, TLR3, TNF-α, TNF RI, TNF RII and VEGF. This human CXCL3 / GRO gamma ELISA Kit showed less than 7% reactivity with recombinant human CXCL1, CXCL2 and CXCL4 proteins.
Target Name CXCL3 / GRO gamma
Conjugation HRP
Conjugation Note Read at 450 nm.
Sensitivity 5 pg/ml
Sample Type Serum, plasma and cell culture supernatants
Standard Range 31.25 - 2000 pg/ml
Sample Volume 100 µl
Precision Intra-Assay CV: 6%
Inter-Assay CV: 9%
Alternate Names Macrophage inflammatory protein 2-beta; MIP2-beta; SCYB3; GRO-gamma; Growth-regulated protein gamma; 5-73; GROg; 1-73; MIP2B; C-X-C motif chemokine 3; CINC-2b; GRO3; MIP-2b

Application Instructions

Assay Time ~ 3 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2921 Human CXCL3

Swiss-port # P19876 Human C-X-C motif chemokine 3

Gene Symbol CXCL3
Gene Full Name chemokine (C-X-C motif) ligand 3
Background This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014]
Function Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. [UniProt]
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PTM N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. [UniProt]
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