ARG81245

Human Eotaxin ELISA Kit

Human Eotaxin ELISA Kit for ELISA and Human

Overview

Product Description

ARG81245 Human Eotaxin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Eotaxin in serum and plasma.

Tested Reactivity Hu
Tested Application ELISA
Target Name Eotaxin
Conjugation HRP
Conjugation Note

Substrate: TMB and read at 450 nm

Sensitivity 0.016 ng/ml
Sample Type Serum and plasma.
Standard Range 0.016 - 1 ng/ml
Sample Volume 100 µl
Alternate Names SCYA11; C-C motif chemokine 11; Eosinophil chemotactic protein; Eotaxin; Small-inducible cytokine A11

Application Instructions

Assay Time ~ 5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6356 Human CCL11

Swiss-port # P51671 Human Eotaxin

Gene Symbol CCL11
Gene Full Name chemokine (C-C motif) ligand 11
Background This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
Function In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. [UniProt]
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PTM O-linked glycan consists of a Gal-GalNAc disaccharide which is modified with up to 2 sialic acid residues.
Title Download Link
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