ARG82951

Human Eotaxin ELISA Kit

Human Eotaxin ELISA Kit for ELISA and Human

Overview

Product Description ARG82951 Human Eotaxin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Eotaxin in serum, plasma and cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Target Name Eotaxin
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Protein Full Name Eotaxin
Sensitivity 2.35 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 4.69 - 300 pg/ml
Sample Volume 100 μl
Precision Intra-Assay CV: < 10%
Inter-Assay CV: < 10%
Alternate Names SCYA11; C-C motif chemokine 11; Eosinophil chemotactic protein; Eotaxin; Small-inducible cytokine A11

Application Instructions

Assay Time ~ 3.5 hours

Properties

Form 96 well
Storage Instruction 4°C
Note Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.

Bioinformation

Gene Symbol CCL11
Gene Full Name chemokine (C-C motif) ligand 11
Background This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]
Function In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. [UniProt]
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PTM O-linked glycan consists of a Gal-GalNAc disaccharide which is modified with up to 2 sialic acid residues.