ARG70118
Human FGF11 (isoform 2) recombinant protein (Active) (His-tagged, C-ter)
Human FGF11 (isoform 2) recombinant protein (Active) (His-tagged, C-ter) for SDS-PAGE
Overview
| Product Description | E. coli expressed, His-tagged (C-ter) Active Human FGF11 (isoform 2) recombinant protein |
|---|---|
| Tested Application | SDS-PAGE |
| Target Name | FGF11 (isoform 2) |
| Species | Human |
| A.A. Sequence | MSLSP EPQLK GIVTK LFCRQ GFYLQ ANPDG SIQGT PEDTS SFTHF NLIPV GLRVV TIQSA KLGHY MAMNA EGLLY SSPHF TAECR FKECV FENYY VLYAS ALYRQ RRSGR AWYLG LDKEG QVMKG NRVKK TKAAA HFLPK LLEVA MYQEP SLHSV PEASP SSPPA P with polyhistidine tag at the C-terminus. |
| Expression System | E. coli |
| Activity | Active |
| Activity Note | Determined by its ability to induce 3T3 cells proliferation. The ED50 for this effect is < 1 ng/ml. |
| Alternate Names | FHF-3; Fibroblast growth factor homologous factor 3; Fibroblast growth factor 11; FGF-11; FHF3 |
Properties
| Form | Powder |
|---|---|
| Purification | Ni-NTA chromatography. |
| Purification Note | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| Purity | > 98% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) |
| Reconstitution | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 µg/ml and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| Storage Instruction | Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | FGF11 |
|---|---|
| Gene Full Name | fibroblast growth factor 11 |
| Background | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this gene has not yet been determined. The expression pattern of the mouse homolog implies a role in nervous system development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| Function | Probably involved in nervous system development and function. [UniProt] |
