ARG83033
Human FGF19 ELISA Kit
Human FGF19 ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83033 Human FGF19 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human FGF19 in serum, plasma (heparin), ascites, urine and cell culture supernatants. |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | Not cross-reacts with: Human bFGF, FGF-21, FGF R1 alpha,FGF-R1 beta, FGF-R2 alpha, FGF-R2 beta. Mouse FGF15, FGF21, FGF23, FGFR1 alpha, FGFR1 beta. Rat FGF15, FGF21, FGF23, FGFR1 alpha, FGFR1 beta. |
| Target Name | FGF19 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Protein Full Name | Fibroblast growth factor 19 |
| Sensitivity | 15.6 pg/ml |
| Sample Type | Serum, plasma (heparin), ascites, urine and cell culture supernatants. |
| Standard Range | 31.3 - 2000 pg/ml |
| Sample Volume | 100 µl |
| Precision | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| Alternate Names | FGF19, FGF 19, Fibroblast Growth Factor 19 |
Application Instructions
| Assay Time | ~ 4 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
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| Gene Symbol | FGF19 |
| Gene Full Name | Fibroblast Growth Factor 19 |
| Background | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008] |
| Function | Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Highlight | Related products: FGF19 antibodies; FGF19 ELISA Kits; FGF19 recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| PTM | Disulfide bond. [UniProt] |
| Title | Download Link |
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| ARG83033 Human FGF19 ELISA Kit User manual |
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