ARG81356
Human HDGF ELISA Kit
Human HDGF ELISA Kit for ELISA and Human
Publication2
Overview
| Product Description | ARG81356 Human HDGF ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human HDGF in serum, plasma and cell culture supernatant. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | HDGF |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | ~ 30 pg/ml |
| Sample Type | Serum, plasma and cell culture supernatant. |
| Standard Range | 78 - 5000 pg/ml |
| Sample Volume | 50 µl |
| Alternate Names | HMG1L2; HMG-1L2; HDGF; High mobility group protein 1-like 2; Hepatoma-derived growth factor |
Application Instructions
| Assay Time | ~ 3.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | HDGF |
| Gene Full Name | hepatoma-derived growth factor |
| Background | HDGF is a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2016] |
| Function | HDGF Isoform 1: Acts as a transcriptional repressor (PubMed:17974029). Has mitogenic activity for fibroblasts (PubMed:11751870, PubMed:26845719). Heparin-binding protein (PubMed:15491618). Isoform 2: Does not have mitogenic activity for fibroblasts (PubMed:26845719). Does not bind heparin (PubMed:26845719). Isoform 3: Has mitogenic activity for fibroblasts (PubMed:26845719). Heparin-binding protein (PubMed:26845719). [UniProt] |
| Highlight | Related products: HDGF antibodies; HDGF ELISA Kits; Related news: The most sensitive human HDGF ELISA kit The role of HDGF in tumor angiogenesis New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| PTM | Sumoylated with SUMO1. Sumoylation prevents binding to chromatin. [UniProt] |
Specific References
HDGF enhances VEGF-dependent angiogenesis and FGF-2 is a VEGF-independent angiogenic factor in non-small cell lung cancer.
ELISA / Human / Cell culture supernatant
HDGF supports anti-apoptosis and pro-fibrosis in pancreatic stellate cells of pancreatic cancer.
ELISA / Human
| Title | Download Link |
|---|---|
| ARG81356 Human HDGF ELISA Kit User's manual |
 Download
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