ARG82986

Human IL10 ELISA Kit

Human IL10 ELISA Kit for ELISA and Human

Cancer kit; Immune System kit

Overview

Product Description ARG82986 Human IL10 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IL10 in Serum, Plasma, Cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Target Name IL10
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm
Protein Full Name Interleukin-10
Sensitivity 4 pg/ml
Sample Type Serum, Plasma, Cell culture supernatants
Standard Range 7.8 - 500 pg/ml
Sample Volume 50 µl
Alternate Names IL10A; GVHDS; TGIF; IL-10; Cytokine synthesis inhibitory factor; CSIF; Interleukin-10

Application Instructions

Assay Time ~4.5 hours

Properties

Form 96 well
Storage Instruction Store components at 4°C or -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3586 Human IL10

Swiss-port # P22301 Human Interleukin-10

Gene Symbol IL10
Gene Full Name interleukin 10
Background The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
Function Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. [UniProt]
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Research Area Cancer kit; Immune System kit
Title Download Link
ARG82986 Human IL10 ELISA Kit User manual download icon Download