ARG80139
Human IL11 ELISA Kit
Human IL11 ELISA Kit for ELISA and Human
Cancer kit; Cell Biology and Cellular Response kit; Developmental Biology kit; Immune System kit
Component
| Cat No | Component Name | Package | Temp |
|---|---|---|---|
| ARG80139-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG80139-002 | Standard (Lyophilized) | 2 X 2.5 ng/vial | 4°C |
| ARG80139-003 | Standard diluent buffer | 20 ml | 4°C |
| ARG80139-004 | Antibody conjugate concentrate | 400 µl | 4°C |
| ARG80139-005 | Antibody diluent buffer | 16 ml | 4°C |
| ARG80139-006 | HRP-Streptavidin concentrate | 400 µl | 4°C (Protect from light) |
| ARG80139-007 | HRP-Streptavidin diluent buffer | 16 ml | 4°C |
| ARG80139-008 | 20X Wash buffer | 50 ml | 4°C |
| ARG80139-009 | TMB substrate | 12ml | 4°C (Protect from light) |
| ARG80139-010 | STOP solution | 12ml | 4°C |
| ARG80139-011 | Plate sealer | 4 strips | Room temperature |
Overview
| Product Description | ARG80139 Human IL11 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IL11 in Serum, Plasma, Cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | No significant cross-reactivity or interference with Human Cardiotrophin-1, IL-6, OSM, CNTF, LIF, G-CSF Leptin |
| Target Name | IL11 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm |
| Sensitivity | 15 pg/ml |
| Sample Type | Serum, Plasma, Cell culture supernatants |
| Standard Range | 31.25 - 2000 pg/ml |
| Sample Volume | 100 µl |
| Precision | CV: <10% |
| Alternate Names | Oprelvekin; Interleukin-11; AGIF; Adipogenesis inhibitory factor; IL-11 |
Application Instructions
| Assay Time | 4 hours |
|---|
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | IL11 |
|---|---|
| Gene Full Name | interleukin 11 |
| Background | The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012] |
| Function | Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. [UniProt] |
| Highlight | Related products: IL11 antibodies; IL11 ELISA Kits; Related news: LKB1 deficiency in T cells promotes gut tumors New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Research Area | Cancer kit; Cell Biology and Cellular Response kit; Developmental Biology kit; Immune System kit |
| Title | Download Link |
|---|---|
| ARG80139 Human IL11 ELISA Kit User's manual |
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