ARG81261
Human IL6R alpha ELISA Kit
Human IL6R alpha ELISA Kit for ELISA and Human
Overview
| Product Description | ARG81261 Human IL6R alpha ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IL6R alpha in serum, plasma or cell culture supernatants. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | IL6R alpha |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 7 pg/ml |
| Sample Type | Serum, plasma or cell culture supernatants. |
| Standard Range | 15.6 - 1000 pg/ml |
| Sample Volume | 100 µl |
| Alternate Names | IL-6R-alpha; CD126; IL6RA; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL6Q; CD antigen CD126; IL-6R 1; IL-6RA; gp80; IL6RQ; Interleukin-6 receptor subunit alpha; IL-6R-1; Membrane glycoprotein 80 |
Application Instructions
| Assay Time | ~ 3.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P08887 Human Interleukin-6 receptor subunit alpha |
|---|---|
| Gene Symbol | IL6R |
| Gene Full Name | interleukin 6 receptor |
| Background | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011] |
| Function | Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity. [UniProt] |
| Highlight | Related products: IL6R alpha antibodies; IL6R alpha ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| PTM | A short soluble form may also be released from the membrane by proteolysis. |
| Title | Download Link |
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| ARG81261 Human IL6R alpha ELISA Kit User's manual |
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