ARG81153

Human IgD ELISA Kit

Human IgD ELISA Kit for ELISA and Human

Overview

Product Description

ARG81153 Human IgD ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IgD in serum, plasma, cell culture, urine, saliva and milk.

Tested Reactivity Hu
Tested Application ELISA
Target Name IgD
Conjugation Note

Substrate: read at 450 nm

Sensitivity 0.03 ng/ml
Sample Type Serum, plasma, cell culture, urine, saliva and milk.
Standard Range 0.0625 - 2 ng/ml
Sample Volume 50 µl
Alternate Names Immunoglobulin D

Application Instructions

Assay Time ~ 4 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol IGHD
Gene Full Name immunoglobulin heavy constant delta
Function IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. [UniProt]
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Title Download Link
ARG81153 Human IgD ELISA Kit User manual download icon Download