ARG30336
Human MDSC Marker Antibody Duo
Myeloid-derived suppressor cells marker; MDSCs marker; Tumor immune microenvironment; tumor-associated myeloid cells
Publication2
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG22000 | anti-CD11b antibody [M1/70] | Rat mAb | Bb, Hu, Ms, R. Mk | BL, FACS, ICC/IF, IHC-Fr, IP | 50 μg |
| ARG65560 | anti-CD33 antibody [WM53] | Mouse mAb | Hu, NHuPrm | CyTOF®-candidate, FACS, FuncSt, ICC/IF, IHC-Fr, IP, WB | 50 μg |
Overview
| Product Description | Human MDSC Marker Antibody Duo includes antibodies to MDSC marker, CD11b and CD33, for Myeloid-derived suppressor cells (MDSCs) study. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immune cells from the myeloid lineage. MDSCs are well-known key negative regulators of the immune response in tumor microenvironment. Accumulated evidences show that MDSCs may serve as a therapeutic target for preventing tumor progression.In humam, MDSCs are defined as cells expressing CD33 and CD11b. arigo’s Human MDSC Marker Antibody Duo comprises CD33 and CD11b antibodies. It is the best solution to identify the MDSCs in human tumor tissues. Related news: New antibody panels and duos for Tumor immune microenvironment Anti-SerpinB9 therapy, a new strategy for cancer therapy |
|---|---|
| Target Name | Human MDSC marker |
| Alternate Names | Human MDSC Marker antibody; Myeloid-derived suppressor cells marker antibody; MDSCs marker antibody; CD11b antibody; CD33 antibody |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | Human Myeloid-derived suppressor cell (MDSC) marker Antibody Duo |
|---|---|
| Highlight | Related products: MDSC Duos / Panels; |
| Research Area | Myeloid-derived suppressor cells marker; MDSCs marker; Tumor immune microenvironment; tumor-associated myeloid cells |
Specific References
Integrin CD11b Contributes to Hypertension and Vascular Dysfunction Through Mediating Macrophage Adhesion and Migration
ARG22000:WB / Mouse
CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization
Mouse / ARG22000: IHC-P, WB
