ARG82629
Human MMP7 Assay Kit
Human MMP7 Assay Kit for Functional study and Human
Overview
| Product Description | ARG82629 Human MMP7 Assay Kit is a detection kit for the quantification of Human MMP7 in serum, urine, tissue homogenates and cell culture supernatants. |
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| Tested Reactivity | Hu |
| Tested Application | FuncSt |
| Specificity | Measures endogenous active MMP7 (naturally occurring) or total active MMP7 (following activation with APMA). |
| Target Name | MMP7 |
| Conjugation Note | Read at 405 nm. |
| Sensitivity | 30 pg/ml for 3 hours incubation 4 pg/ml for 25 hours incubation |
| Detection Range | 4 - 16000 pg/ml |
| Sample Type | Serum, urine, tissue homogenates and cell culture supernatants. |
| Sample Volume | 100 µl |
| Alternate Names | MMP-7; Uterine metalloproteinase; Matrix metalloproteinase-7; EC 3.4.24.23; Matrilysin; Matrin; Pump-1 protease; PUMP-1; MPSL1 |
Application Instructions
| Assay Time | Overnight |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MMP7 |
| Gene Full Name | matrix metallopeptidase 7 |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] |
| Function | Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. [UniProt] |
| Cellular Localization | Secreted, extracellular space, extracellular matrix. [UniProt] |
| Title | Download Link |
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| ARG82629 Human MMP7 Assay kit User manual |
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