ARG82630
Human MMP8 Assay Kit
Human MMP8 Assay Kit for Functional study and Human
Publication1
Overview
| Product Description | ARG82630 Human MMP8 Assay Kit is a detection kit for the quantification of Human MMP8 in serum, plasma, cell culture supernatants, urine, saliva and tissue homogenates. |
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| Tested Reactivity | Hu |
| Tested Application | FuncSt |
| Specificity | Measures endogenous active MMP8 (naturally occurring) or total active MMP8 (following activation with APMA). |
| Target Name | MMP8 |
| Conjugation Note | Read at 405 nm. |
| Sensitivity | 100 pg/ml for 2 hours incubation 24 pg/ml for 6 hours incubation 4 pg/ml for 24 hours incubation |
| Detection Range | 10 - 24000 pg/ml |
| Sample Type | Serum, plasma, cell culture supernatants, urine, saliva and tissue homogenates. |
| Sample Volume | 100 µl |
| Alternate Names | HNC; PMNL collagenase; MMP-8; PMNL-CL; CLG1; Neutrophil collagenase; Matrix metalloproteinase-8; EC 3.4.24.34 |
Application Instructions
| Assay Time | Overnight |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MMP8 |
| Gene Full Name | matrix metallopeptidase 8 |
| Background | This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
| Function | Can degrade fibrillar type I, II, and III collagens. [UniProt] |
| Cellular Localization | Cytoplasmic granule. Secreted, extracellular space, extracellular matrix. Note=Stored in intracellular granules. [UniProt] |
Specific References
Adipose-derived stem cells enriched with therapeutic mRNA TGF-β3 and IL-10 synergistically promote scar-less wound healing in preclinical models
ELISA / Human / Culture supernatant
| Title | Download Link |
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| ARG82630 Human MMP8 Assay kit kit User manual |
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