ARG82594
Human OSMR ELISA Kit
Human OSMR ELISA Kit for ELISA and Human
Overview
| Product Description | ARG82594 Human OSMR ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human OSMR in serum, plasma and cell culture supernatants. |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | This kit could assay both natural and recombinant Human OSMR. No significant cross-reactivity or interference was observed in the following samples: Human: IFN gamma, IL1 beta, IL2, IL4, IL5, IL6, IL8, IL10, IL12, IL17A, IL18, IL21, IL22, IL23, MCP1, TGF beta 1, TNF alpha and VEGF. Mouse: GM-CSF, IFN gamma, IL1 beta, IL2, IL4, IL6, IL10, IL17A and TNF alpha. Rat: IFN gamma, IL1 beta, IL4, IL6, IL10 and TNF alpha. |
| Target Name | OSMR |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 0.12 ng/ml |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 0.23 - 15 ng/ml |
| Sample Volume | 10 - 100 µl |
| Precision | Intra-Assay CV: 3.1% Inter-Assay CV: 2.5% |
| Alternate Names | OSMRB; IL-31RB; Oncostatin-M-specific receptor subunit beta; Interleukin-31 receptor subunit beta; IL-31 receptor subunit beta; PLCA1; IL-31R-beta; IL-31R subunit beta |
Application Instructions
| Assay Time | ~ 3.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q99650 Human Oncostatin-M-specific receptor subunit beta |
|---|---|
| Gene Symbol | OSMR |
| Gene Full Name | oncostatin M receptor |
| Background | This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
| Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. [UniProt] |
| Cellular Localization | Membrane; Single-pass type I membrane protein. [UniProt] |
| Highlight | Related products: New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Title | Download Link |
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| ARG82594 Human OSMR ELISA Kit User manual |
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