ARG83340
Human PIGR ELISA Kit
Human PIGR ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83340 Human PIGR ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human PIGR in serum, plasma and cell culture supernatants. |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | PIGR |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 150 pg/ml |
| Detection Range | 312 pg/ml - 20000 pg/ml |
| Sample Type | Serum, Plasma and Cell culture supernatants. |
| Alternate Names | Polymeric immunoglobulin receptor; Hepatocellular carcinoma-associated protein TB6; PIgR; Poly-Ig receptor |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PIGR |
| Gene Full Name | polymeric immunoglobulin receptor |
| Background | This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009] |
| Function | This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. [UniProt] |
| Cellular Localization | Cell membrane, Single-pass type I membrane protein, Secreted. [UniProt] |
| PTM | N-glycosylation is not necessary for Ig binding. [UniProt] |
| Title | Download Link |
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| ARG83340 Human PIGR ELISA Kit User manual |
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