ARG82251

Human S100A6 ELISA Kit

Human S100A6 ELISA Kit for ELISA and Human

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Overview

Product Description ARG82251 Human S100A6 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human S100A6 in serum, plasma and cell culture supernatants.
Tested Reactivity Hu
Tested Application ELISA
Specificity Not react with following recombinant human proteins: ApoAI, BMP1, BMP2, BMP3, BMP4, BMP7, CRP, HGF, HSP27, IL1 alpha, IL1 RI, IL1 beta, IL1RA, IL2, IL4, IL5, IL6, IL8, IL10, IL12, IL13, IL15, IL17C, IL21, IL23, IFN gamma, MMP2, sIL2R, sIL6R, PDGF, PLA2G7, prolactin, S100A1, S100B, S100A9, S100A12, TGF beta 1, TGF beta 2, TGF beta 3, TLR1, TLR2, TLR3, TNF alpha, TNF RI, TNF RII and VEGF.
Target Name S100A6
Conjugation HRP
Conjugation Note Read at 450 nm.
Sensitivity 31 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 62 - 4000 pg/ml
Sample Volume 100 µl
Precision Intra-Assay CV: 6%
Inter-Assay CV: 9%
Alternate Names S100 calcium-binding protein A6; PRA; MLN 4; 5B10; Prolactin receptor-associated protein; CACY; Growth factor-inducible protein 2A9; Protein S100-A6; Calcyclin; CABP; 2A9

Application Instructions

Assay Time ~ 3 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 6277 Human S100A6

Swiss-port # P06703 Human Protein S100-A6

Gene Symbol S100A6
Gene Full Name S100 calcium binding protein A6
Background The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]
Function May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. [UniProt]
Cellular Localization Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. [UniProt]
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PTM The N-terminus is blocked. [UniProt]

Specific References

S100A6 participates in initiation of autoimmune encephalitis and is under epigenetic control

ELISA / Human

Chih-Hsiang Lin et al.
Brain Behav.,  (2023)

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S100A6 Promotes B Lymphocyte Penetration Through the Blood-Brain Barrier in Autoimmune Encephalitis.

ELISA / Human

Tsai Meng-Han et al.
Front Genet.,  (2019)

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Title Download Link
ARG82251 Human S100A6 ELISA Kit User manual download icon Download