ARG80762
Human Serpin E1 / PAI1 ELISA Kit
Human Serpin E1 / PAI1 ELISA Kit for ELISA and Human
Cancer kit; Cell Biology and Cellular Response kit; Metabolism kit
Overview
Product Description | ARG80762 Human Serpin E1 / PAI1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Serpin E1 / PAI1 in Serum, Plasma (EDTA), Cell culture supernatants. |
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Tested Reactivity | Hu |
Tested Application | ELISA |
Specificity | No cross-reacts with human tPa, uPAR, uPA, Vitronectin, Serpin A1, A3, A4, A5, C1, D1, E2, F2, G1 |
Target Name | PAI1 / SERPINE1 |
Sensitivity | 24 pg/ml |
Sample Type | Serum, Plasma (EDTA), Cell culture supernatants |
Standard Range | 46.8 - 3000 pg/ml |
Sample Volume | 100 μl |
Precision | <10% |
Alternate Names | Serpin E1; PLANH1; Endothelial plasminogen activator inhibitor; Plasminogen activator inhibitor 1; PAI; PAI1; PAI-1 |
Properties
Form | 96 well |
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Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | SERPINE1 |
Gene Full Name | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
Background | Serpin E1 is a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
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Research Area | Cancer kit; Cell Biology and Cellular Response kit; Metabolism kit |
PTM | Inactivated by proteolytic attack of the urokinase-type (u-PA) and the tissue-type (TPA), cleaving the 369-Arg-|-Met-370 bond. |
Title | Download Link |
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ARG80762 Human Serpin E1 / PAI1 ELISA Kit User's manual | Download |