ARG80762

Human Serpin E1 / PAI1 ELISA Kit

Human Serpin E1 / PAI1 ELISA Kit for ELISA and Human

Cancer kit; Cell Biology and Cellular Response kit; Metabolism kit

Overview

Product Description

ARG80762 Human Serpin E1 / PAI1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Serpin E1 / PAI1 in Serum, Plasma (EDTA), Cell culture supernatants.

Tested Reactivity Hu
Tested Application ELISA
Specificity No cross-reacts with human tPa, uPAR, uPA, Vitronectin, Serpin A1, A3, A4, A5, C1, D1, E2, F2, G1
Target Name PAI1 / SERPINE1
Sensitivity 24 pg/ml
Sample Type Serum, Plasma (EDTA), Cell culture supernatants
Standard Range 46.8 - 3000 pg/ml
Sample Volume 100 μl
Precision

<10%

Alternate Names Serpin E1; PLANH1; Endothelial plasminogen activator inhibitor; Plasminogen activator inhibitor 1; PAI; PAI1; PAI-1

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5054 Human SERPINE1

Swiss-port # P05121 Human Plasminogen activator inhibitor 1

Gene Symbol SERPINE1
Gene Full Name serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Background Serpin E1 is a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
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Research Area Cancer kit; Cell Biology and Cellular Response kit; Metabolism kit
PTM Inactivated by proteolytic attack of the urokinase-type (u-PA) and the tissue-type (TPA), cleaving the 369-Arg-|-Met-370 bond.
Title Download Link
ARG80762 Human Serpin E1 / PAI1 ELISA Kit User's manual download icon Download