ARG80785

Human hCG beta (free) ELISA Kit

Human hCG beta (free) ELISA Kit for ELISA and Human

Cancer kit; Developmental Biology kit; Metabolism kit; Signaling Transduction kit

Overview

Product Description ARG80785 Human hCG beta (free) ELISA Kit is an enzyme immunoassay kit for the quantification of free beta subunit of human chorionic gonadotropin (free β-hCG) in serum and plasma (EDTA).
Tested Reactivity Hu
Tested Application ELISA
Target Name hCG beta (free)
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm
Sensitivity 0.2 ng/ml
Sample Type Serum and plasma (EDTA).
Standard Range 10 - 200 ng/ml
Sample Volume 50 µl
Alternate Names hCGB; CGB5; CGB7; CGB3; Chorionic gonadotrophin chain beta; CGB8; CG-beta; Choriogonadotropin subunit beta

Application Instructions

Assay Time 30, 30 min (37°C), 20 min (RT)

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1082 Human CGB

Swiss-port # P01233 Human Choriogonadotropin subunit beta

Gene Symbol CGB
Gene Full Name chorionic gonadotropin, beta polypeptide
Background Human Chorionic Gonadotropin (hCG) is a glycoprotein hormone normally produced by placenta during pregnancy. The hormone is present in blood and urine around seven to thirteen days following implantation of the fertilized ovum. Structurally intact hCG molecules consist of two non-covalently linked polypeptide subunits, the alpha and beta chain subunits. Measurement of intact hCG and of the alpha subunit of hCG appears to give similar results in blood and urine but not the levels of beta subunit.

The measurement of free β-HCG in the first trimester of pregnancy has been reported as a useful marker in antenatal screening for Down Syndrome and other fetal aneuploidies. Increased free β-HCG values in combination with maternal age, the measurement of PAPP-A and the ultrasonic determination of nuchal translucency (NT) in pregnancy weeks 11 to 14 may detect up to 90 % of pregnancies with Down syndrom
Function Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. [UniProt]
Cellular Localization Secreted. [UniProt]
Highlight Related products:
hCG beta antibodies; hCG beta ELISA Kits; hCG beta Duos / Panels;
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Research Area Cancer kit; Developmental Biology kit; Metabolism kit; Signaling Transduction kit
Title Download Link
ARG80785 Human Free beta hCG ELISA Kit User's manual download icon Download