ARG81078
Human plasminogen (total) ELISA Kit
Human plasminogen (total) ELISA Kit for ELISA and Human
Cancer kit; Cell Biology and Cellular Response kit
Component
| Cat No | Component Name | Package | Temp |
|---|---|---|---|
| ARG81078-001 | Antibody-coated microplate | 1 plate (96 well) | 4°C |
| ARG81078-002 | 10X Wash buffer | 50 ml | 4°C |
| ARG81078-003 | Human Plasminogen standard | 1 vial (Lyophilized) | 4°C |
| ARG81078-004 | Anti-Human Plasminogen primary antibody | 1 vial (Lyophilized) | 4°C |
| ARG81078-005 | HRP-conjugated secondary antibody | 1 vial (concentrated) | 4°C |
| ARG81078-006 | TMB substrate | 10 ml | 4°C (Protect from light) |
Overview
| Product Description | ARG81078 Human plasminogen (total) ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human plasminogen (total) in plasma, serum and cell culture media. |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | plasminogen |
| Conjugation | HRP |
| Conjugation Note | TMB substrate is used for color development at 450 nm. |
| Sensitivity | 0.11 ng/ml |
| Detection Range | 0.5 - 500 ng/ml |
| Sample Type | Plasma, serum and cell culture media |
| Alternate Names | EC 3.4.21.7; Plasminogen |
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PLG |
| Gene Full Name | plasminogen |
| Background | The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009] |
| Function | Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo. [UniProt] |
| Highlight | Related products: Plasminogen antibodies; Plasminogen ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Research Area | Cancer kit; Cell Biology and Cellular Response kit |
| PTM | N-linked glycan contains N-acetyllactosamine and sialic acid. O-linked glycans consist of Gal-GalNAc disaccharide modified with up to 2 sialic acid residues (microheterogeneity). In the presence of the inhibitor, the activation involves only cleavage after Arg-580, yielding two chains held together by two disulfide bonds. In the absence of the inhibitor, the activation involves additionally the removal of the activation peptide. |
| Title | Download Link |
|---|---|
| ARG81078 Human plasminogen (total) ELISA Kit User manual |
 Download
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