ARG82771
MPO / Myeloperoxidase Assay Kit (Fluorometric)
MPO / Myeloperoxidase Assay Kit (Fluorometric) for Functional study and All species,Human,Mouse,Rat
Overview
| Product Description | ARG82771 MPO / Myeloperoxidase Assay Kit (Fluorometric) is a detection kit for the quantification of Myeloperoxidase peroxidation in cell lysate and tissue. |
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| Tested Reactivity | Hu, Ms, Rat, All |
| Tested Application | FuncSt |
| Target Name | MPO / Myeloperoxidase |
| Conjugation Note | λ ex/em = 530 / 585 nm (fluorometric) |
| Sensitivity | 0.0025 U/L |
| Detection Range | 0.0025 - 2 U/L |
| Sample Type | Cell lysate and tissue. |
| Sample Volume | 20 µl |
| Alternate Names | MPO; Myeloperoxidase; EC 1.11.2.2 |
Application Instructions
| Application Note | Please note that this kit does not include a microplate. |
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| Assay Time | < 1 hour |
Properties
| Form | Liquid |
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| Storage Instruction | Store the kit at -20°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | MPO |
| Gene Full Name | myeloperoxidase |
| Background | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014] |
| Function | Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. [UniProt] |
| Cellular Localization | Lysosome. [UniProt] |
| Title | Download Link |
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| ARG82771 MPO / Myeloperoxidase Assay Kit (Fluorometric) User manual |
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