ARG30106

Mitochondria/Caspase Dependant Apoptosis Marker Antibody Duo (Caspase9, Cytochrome c)

Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody; Signaling Transduction antibody
publication_link Publication2

Component

Cat No Component Name Host clonality Reactivity Application Package
ARG20048 anti-Caspase 9 (cleaved) antibody Rabbit pAb Hu IP, WB 25 μg
ARG20006 anti-Cytochrome C antibody Rabbit pAb Bov, Chk, Dog, Hu, Ms, Rat IP, WB 25 μg

Overview

Product Description Cytochrome C is an electron transport protein localized in the mitochondria. When a cell receive intra- or extra-cellular death signal, Cytochrome C is then released from mitochondria to cytoplasm and trigger Procaspase 9 activation. Detection of the cytoplasmic release of Cytochrome C and activation of Caspase 9 with anti-Cytochrome C (ARG20006) and anti-Caspase 9 (ARG51317) antibodies are early indications that a cell is undergoing apoptosis.
Target Name Mitochondria/Caspase Dependant Apoptosis Marker
Alternate Names Mitochondria/Caspase Dependant Apoptosis Marker antibody; Cytochrome C antibody; Caspase 9 (cleaved) antibody

Properties

Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Full Name Antibody Duo for Mitochondria/Caspase Dependant Apoptosis Marker (Caspase9, Cytochrome c)
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody; Signaling Transduction antibody

Specific References

Single-Cell Analysis of Signaling Proteins Provides Insights into Proapoptotic Properties of Anticancer Drugs.

ARG20006: scPISA / Human

Yanrong Wen et al.
Anal Chem.,  (2020)

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Probing apoptosis signaling proteins in single living cells for precision efficacy evaluation of anti-cancer drugs.

ARG20006: / Human

Wen Yanrong et al.
Preprint.,  (2019)

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