ARG82665
Monkey IL1RA ELISA Kit
Monkey IL1RA ELISA Kit for ELISA and Monkey
Overview
Product Description | ARG82665 Monkey IL1RA ELISA Kit is an Enzyme Immunoassay kit for the quantification of Monkey IL1RA in serum, plasma and cell culture supernatants. |
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Tested Reactivity | Mk |
Tested Application | ELISA |
Target Name | IL1RA |
Conjugation | HRP |
Conjugation Note | Substrate: TMB and read at 450 nm. |
Sensitivity | 23.5 pg/ml |
Sample Type | Serum, plasma and cell culture supernatants. |
Standard Range | 46.9 - 3000 pg/ml |
Sample Volume | 100 µl |
Precision | CV: less than 10% |
Alternate Names | IL1 inhibitor; Interleukin-1 receptor antagonist protein; ICIL-1RA; MVCD4; IL1RA; DIRA; IL-1RN; Anakinra; IL1F3; IRAP; IL-1ra; IL-1ra3 |
Application Instructions
Assay Time | ~ 3.5 hours |
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Properties
Form | 96 well |
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Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Gene Symbol | IL1RN |
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Gene Full Name | interleukin 1 receptor antagonist |
Background | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jan 2016] |
Function | Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. [UniProt] |
Cellular Localization | Isoform 1: Secreted. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm. Isoform 4: Cytoplasm. [UniProt] |
Highlight | Related products: IL1RA antibodies; IL1RA ELISA Kits; IL1RA recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
Title | Download Link |
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ARG82665 Monkey IL1RA ELISA kit User's manual | Download |