ARG82965

Mouse CCL2 / MCP1 (High sensitive) ELISA kit

Mouse CCL2 / MCP1 (High sensitive) ELISA kit for ELISA and Mouse

Cancer kit; Cell Biology and Cellular Response kit; Immune System kit; Metabolism kit

Overview

Product Description ARG82965 Mouse CCL2 / MCP1 (High sensitive) ELISA kit is an Enzyme Immunoassay kit for the quantification of Mouse CCL2 / MCP1 in serum, plasma and cell culture supernatants.
Tested Reactivity Ms
Tested Application ELISA
Target Name CCL2 / MCP1
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Protein Full Name C-C motif chemokine 2
Sensitivity 1.95 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 3.9 - 250 pg/ml
Sample Volume 100 μl
Precision Intra-Assay CV: < 10%
Inter-Assay CV: < 10%
Alternate Names MCP1; Monocyte chemotactic and activating factor; MCAF; Monocyte chemotactic protein 1; Monocyte secretory protein JE; HSMCR30; Small-inducible cytokine A2; HC11; SMC-CF; GDCF-2; SCYA2; C-C motif chemokine 2; Monocyte chemoattractant protein 1; MCP-1

Application Instructions

Assay Time ~ 3.5 hours

Properties

Form 96 well
Storage Instruction 4°C
Note Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.

Bioinformation

Gene Symbol Ccl2
Gene Full Name chemokine (C-C motif) ligand 2
Background This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008]
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Research Area Cancer kit; Cell Biology and Cellular Response kit; Immune System kit; Metabolism kit
PTM Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant.
Title Download Link
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