ARG82060

Mouse CXCL11 / I-TAC ELISA Kit

Mouse CXCL11 / I-TAC ELISA Kit for ELISA and Mouse

Overview

Product Description Mouse CXCL11 / I-TAC ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse CXCL11 / I-TAC in serum, plasma and cell culture supernatants.
Tested Reactivity Ms
Tested Application ELISA
Target Name CXCL11 / I-TAC
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 60 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 125 - 8000 pg/ml
Sample Volume 100 µl
Alternate Names SCYB9B; SCYB11; C-X-C motif chemokine 11; Beta-R1; b-R1; Interferon gamma-inducible protein 9; I-TAC; Small-inducible cytokine B11; Interferon-inducible T-cell alpha chemoattractant; H174; IP-9; IP9

Application Instructions

Assay Time 4.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 56066 Mouse CXCL11

Swiss-port # Q9JHH5 Mouse C-X-C motif chemokine 11

Gene Symbol CXCL11
Gene Full Name chemokine (C-X-C motif) ligand 11
Background Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Function Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. [UniProt]
Cellular Localization Secreted. [UniProt]
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