Component

Overview

Product Description	ARG83015 Mouse IL38 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse IL38 in serum, plasma (heparin), ascites, urine and cell culture supernatants.
Tested Reactivity	Ms
Tested Application	ELISA
Specificity	Not cross-reacts with: Human IL1ra, IL1 Rrp, IL31, IL37, IL38. Mouse IL1ra, IL1 Rrp, IL22, IL23, IL27, IL33. Rat IL1ra, IL1 Rrp, IL38.
Target Name	IL38
Conjugation	HRP
Conjugation Note	Substrate: TMB and read at 450 nm.
Protein Full Name	Interleukin-1 family member 10
Sensitivity	0.2 ng/ml
Sample Type	Serum, plasma (heparin), ascites, urine and cell culture supernatants.
Standard Range	0.4 - 30 ng/ml
Sample Volume	100 µl
Precision	Intra-Assay CV: less than 10% Inter-Assay CV: less than 10%
Alternate Names	IL1F10; Interleukin 1 Family Member 10; IL-1HY2; IL1-Theta; IL-1F10; FKSG75; Interleukin-1 Receptor Antagonist FKSG75; Interleukin-1 Family Member 10; Family Of Interleukin 1-Theta; Interleukin-1 HY2; Interleukin-38; FIL1 Theta; IL-1 Theta; MGC119832; MGC119833; MGC11983; IL1HY2; IL-38; Interleukin-1 Receptor Antagonist-Like FIL1 Theta; Interleukin 1 Family, Member 10 (Theta); Interleukin 1 Family Member 10 (Theta); IL-1F10 (Canonical Form IL-1F10a); Interleukin-1 Theta; FIL1- Theta; FIL1-Theta; FIL1T; IL38

Application Instructions

Assay Time	~ 4 hours

Properties

Form	96 well
Storage Instruction	Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 215274 Mouse IL1F10 Swiss-port # Q8R459 Mouse Interleukin-1 family member 10
Gene Symbol	IL1F10
Gene Full Name	Interleukin 1 Family Member 10
Background	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Function	Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2. [Uniprot]
Cellular Localization	Cytoplasm, secreted. [UniProt]
Highlight	Related products: IL38 antibodies; IL38 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData