ARG80907
Mouse IL5 ELISA kit
Mouse IL5 ELISA kit for ELISA and Mouse
Cancer kit; Immune System kit
Publication2
Overview
| Product Description | ARG80907 Mouse IL5 ELISA kit is a Enzyme Immunoassay kit for the quantification of Mouse IL5 in Serum, Plasma, Cell culture supernatants |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ELISA |
| Specificity | No significant cross-reactivity or interference with GM-CSF, IL3, IL5Rα. |
| Target Name | IL5 |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm |
| Sensitivity | 8 pg/ml |
| Sample Type | Serum, Plasma, Cell culture supernatants |
| Standard Range | 15.6 - 1000 pg/ml |
| Sample Volume | 100 µl |
| Precision | CV: <10% |
| Alternate Names | Eosinophil differentiation factor; EDF; IL5; TRF; T-cell replacing factor; B-cell differentiation factor I; Interleukin-5 |
Application Instructions
| Assay Time | 4 hours |
|---|
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | Il5 |
|---|---|
| Gene Full Name | interleukin 5 |
| Background | The IL-5 gene is located on chromosome 11 in the mouse, and chromosome 5 in humans, in close proximity to the genes encoding IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor (GM-CSF), which are often co-expressed in TH2 cells. Interleukin-5 is also expressed by eosinophils[4] and has been observed in the mast cells of asthmatic airways by immunohistochemistry. IL-5 expression is regulated by several transcription factors including GATA3. [IL-5 wiki] IL5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL5 plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of IL5 may be related to pathogenesis of eosinophil-dependent inflammatory diseases. IL5 functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). [provided by RefSeq, Jul 2013] |
| Function | Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. [UniProt] |
| Highlight | Related products: IL5 antibodies; IL5 ELISA Kits; IL5 recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Research Area | Cancer kit; Immune System kit |
Specific References
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ELISA / Mouse
Against NF-κB/thymic stromal lymphopoietin signaling pathway, catechinalleviates the inflammation in allergic rhinitis.
ELISA / Mouse
| Title | Download Link |
|---|---|
| ARG80907 Mouse IL5 ELISA kit User's manual |
 Download
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