ARG82294

Mouse IL6 (High sensitive) ELISA Kit

Mouse IL6 (High sensitive) ELISA Kit for ELISA and Mouse

Overview

Product Description ARG82294 Mouse IL6 (High sensitive) ELISA Kit is a high sensitive Enzyme Immunoassay kit for the quantification of Mouse IL6 in serum, plasma and cell culture supernatants.
Tested Reactivity Ms
Tested Application ELISA
Specificity Not react with recombinant Mouse IL4, IFN gamma, Epo, Fas, GDNF, GITR and GITR Ligand.
Target Name IL6
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm.
Sensitivity 1.56 pg/ml
Sample Type Serum, plasma and cell culture supernatants.
Standard Range 3.125 - 200 pg/ml
Sample Volume 100 µl
Precision Intra-Assay CV: < 9%
Inter-Assay CV: < 9%
Alternate Names B-cell stimulatory factor 2; CDF; HSF; BSF-2; Interferon beta-2; IL-6; IFNB2; CTL differentiation factor; Interleukin-6; HGF; Hybridoma growth factor; BSF2; IFN-beta-2

Application Instructions

Assay Time ~ 3.5 hours

Properties

Form 96 well
Storage Instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 16193 Mouse IL6

Swiss-port # P08505 Mouse Interleukin-6

Gene Symbol IL6
Gene Full Name interleukin 6
Background This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
Function Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. [UniProt]
Cellular Localization Secreted. [UniProt]
Highlight Related products:
IL6 antibodies; IL6 ELISA Kits; IL6 recombinant proteins;
Related news:
HMGB1 in inflammation
Inflammatory Cytokines
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
PTM N- and O-glycosylated. [UniProt]
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