ARG80702
Mouse/Rat IGFI ELISA Kit
Mouse/Rat IGFI ELISA Kit for ELISA and Mouse,Rat
Cancer kit; Developmental Biology kit; Signaling Transduction kit
Overview
| Product Description | ARG80702 Mouse/Rat IGF-I ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse and Rat IGFI in serum and plasma (EDTA, heparin, citrate). |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | ELISA |
| Target Name | IGFI |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | < 0.029 ng/ml |
| Sample Type | Serum and plasma (EDTA, heparin, citrate). |
| Standard Range | 0.5 - 18 ng/ml |
| Sample Volume | 50 µl |
| Alternate Names | Igf-1; Igf-I; Somatomedin; Insulin-like growth factor I; MGF; Mechano growth factor; Somatomedin-C; IGFI; IGF-I |
Properties
| Form | 96 well |
|---|---|
| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Igf1 |
| Gene Full Name | insulin-like growth factor 1 |
| Background | This gene encodes a member of the insulin-like growth factor (IGF) family of proteins that promote growth and development during fetal and postnatal life. This gene is predominantly expressed in the liver and the encoded protein undergoes proteolytic processing to generate a disulfide-linked mature polypeptide. Transgenic disruption of this gene in mice results in reduced postnatal survival and severe growth retardation. Mice lacking the encoded protein exhibit generalized organ hypoplasia including underdevelopment of the central nervous system and developmental defects in bone, muscle and reproductive systems. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015] |
| Function | The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation (By similarity). [UniProt] |
| Highlight | Related products: IGFI antibodies; IGFI ELISA Kits; IGFI Duos / Panels; IGFI recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Research Area | Cancer kit; Developmental Biology kit; Signaling Transduction kit |
| Title | Download Link |
|---|---|
| ARG80702 Mouse/Rat IGFI ELISA Kit User's manual |
 Download
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